Research Publications

Hypoxia activates cadherin-22 synthesis via eIF4E2 to drive cancer cell migration, invasion and adhesion

DNMT3a epigenetic program regulates the HIF-2α oxygen-sensing pathway and the cellular response to hypoxia

An Immunohistochemical Algorithm for Ovarian Carcinoma Typing

Integrated genomic characterization of oesophageal carcinoma

RBM5 reduces small cell lung cancer growth, increases cisplatin sensitivity and regulates key transformation-associated pathways

COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis.

Hexokinase II expression is correlated with colorectal cancer prognosis.

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Cytokines and cell adhesion molecules exhibit distinct profiles in health, ovarian cancer, and breast cancer.

COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation.

A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer.

Biobank bootstrapping: is biobank sustainability possible through cost recovery?

Investigating Ochratoxin A and Biotin Levels in Patients with Renal Carcinoma.

Endogenous biotin expression in renal and testicular tumours and literature review.

A practical tool for modeling biospecimen user fees.

Comprehensive molecular characterization of gastric adenocarcinoma.

Comprehensive molecular profiling of lung adenocarcinoma.

Comprehensive molecular characterization of urothelial bladder carcinoma.

Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer.

Ochratoxin A is not detectable in renal and testicular tumours.

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants.

Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines.

Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.

Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas.

Pharmacologic inhibition of MEK signaling prevents growth of canine hemangiosarcoma.

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.

Cholesterol masks membrane glycosphingolipid tumor-associated antigens to reduce their immunodectection in human cancer biopsies.

Identification of the IGF1/PI3K/NF κB/ERK gene signaling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer.

The use of X-ray interaction data to differentiate malignant from normal breast tissue at surgical margins and biopsy analysis.

Integrated genomic characterization of endometrial carcinoma.

Generating a comprehensive set of standard operating procedures for a biorepository network-The CTRNet experience.

Application of Selected Reaction Monitoring for Multiplex Quantification of Clinically Validated Biomarkers in Formalin-Fixed, Paraffin-Embedded Tumour Tissue.

Kinesin family member 14: An independent prognostic marker and potential therapeutic target for ovarian cancer.

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer.

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.

Intra-protein variability revealed by absolute quantification of plasma proteins using dimethyl labelling.

Investigating Ochratoxin A and Biotin Levels in Patients with Renal Carincoma.

Comprehensive genomic characterization of squamous cell lung cancers.

Embryonic protein nodal promotes breast cancer vascularization.

Proteomic Profiling of a Mouse Model for Ovarian Granulosa Cell Tumor Identifies VCP as a Highly Sensitive Serum Tumor Marker in Several Human Cancers.

Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth.

New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer.

The differentiation of malignant and benign human breast tissue at surgical margins and biopsy using x-ray interaction data and Bayesian classification.

Multilevel whole-genome analysis reveals candidate biomarkers in clear cell renal cell carcinoma.

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses.

Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice.

Oncogenic FAM131B–BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.

NT-proBNP measurement using a multiplex platform in cancer and chest pain populations.

Identification of vascular breast tumour markers by laser capture microdissection and label-free LC-MS.

Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.

miRNA Profiling in Metastatic Renal Cell Carcinoma Reveals a Tumour-Suppressor Effect for miR-215.

Establishing a reference interval for the high sensitive Troponin T assay in treatment-naïve cancer patients.

Identification of a Novel HSP70-binding Cochaperone Critical to HSP90-mediated Activation of Small Serine/Threonine Kinase.

Global Profiling and Molecular Characterization of Alternative Splicing Events Misregulated in Lung Cancer.

Analyzing The Biological Role Of The Transcription Factor Kaiso In Breast Tumourigenesis.

A cancer derived mutation in the Retinoblastoma gene with a distinct defect for LXCXE dependent interactions.

Kaiso regulates Znf131-mediated transcriptional activation.

Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.

An algorithm for classifying tumors based on genomic aberrations and selecting representative tumor models.

Cytokines and cell adhesion molecules exhibit distinct profiles in health, ovarian cancer, and breast cancer.

Amplification of mRNA from Formalin-Fixed Paraffin-Embedded (FFPE) Breast Cancer Tissues without 3' Bias and Multiplex Expression Analysis on Flow-Through Microarrays.

Cytokine elevations in acute coronary syndrome and ovarian cancer: a mechanism for the up-regulation of the acute phase proteins in these different disease etiologies.

Pilot study assessing the utility of an adhesion array and high-sensitivity cytokine array as surrogate biomarkers in ovarian cancer.